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Duration of action zofran
Ondansetron, marketed under the brand name Zofran, is a medication used to prevent nausea …. It is thought that ondansetron's antiemetic action is mediated mostly via antagonism of vagal afferents with a minor contribution from antagonism…Drug action. Ondansetron is a specific 5HT3-receptor antagonist which blocks 5HT3 receptors in the gastro-intestinal tract and in the CNS.The active ingredient in ZOFRAN tablets and ZOFRAN oral solution is …. were transient and did not appear to be related to dose or duration of therapy. ….. While its mechanism of action has not been fully characterized, ondansetron is not a…Medscape – Nausea & vomiting dosing for Zofran, Zuplenz (ondansetron), frequency-based adverse effects, comprehensive interactions, contraindications,…Zofran, Zofran ODT … chemoreceptor trigger zone, it's uncertain if antiemetic action is mediated centrally, peripherally, or both. … Route, Onset, Peak, Duration.Zofran tablets are indicated for the management of nausea and vomiting induced by ….. patients are unlikely to respond due to the anti-emetic action of ondansetron itself. …. Following intramuscular administration of ondansetron, peak plasma…… gastrointestinal tract to exert it's effects. It's onset of action is 30 minutes, and duration of action is 2-7 hours. Zofran is considered safe for use during pregnancy.19 Nov 2009 … Ondansetron. PHARMACOLOGY. 5HT3-receptor antagonist. Onset of action: 30 minutes PO, 5 minutes IV Time to peak: 1-2 h PO Duration of…Ondansetron/Zofran ODT Oral Tab Orally Dis: 4mg, 8mg …… The duration of the antiemetics action may need to be taken into account when selecting the…Ondansetron is a potent and highly selective serotonin 5-HT3-receptor antagonist which … Since the time to reach peak concentration is 0.5 to 2 hours after oral…
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