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Pradaxa can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). This type of blood clot could cause long-term paralysis, and may be more likely to occur if: you have a genetic spinal defect; you have a spinal catheter in place; you have a history of spinal surgery or repeated spinal taps; you have recently had a spinal tap or epidural anesthesia; you are taking an NSAID–Advil, Aleve, Motrin, and others; or you are using other medicines to treat or prevent blood clots.
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