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If you are taking any of these drugs: Reserpine or tetrabenazine. If you have taken certain drugs used for low mood (depression) like isocarboxazid, phenelzine, or tranylcypromine or drugs used for Parkinson’s disease like selegiline or rasagiline in the last 14 days. Taking this medicine within 14 days of those drugs can cause very bad high blood pressure. If you are taking another drug that has the same drug in it. This is not a list of all drugs or health problems that interact with Sinemet.
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